Comprises 3 Hyde Detectors, increased resolution by adaptive deconvolution, climate chamber for live cell imaging

Optical tweezers setup for single molecule mechanics measurements in aequeous solutions with integrated microfluidics with in situ change of solution conditions for one single molecule

Typical applications: study of the mechanics and kinetics of folding and binding of single protein, DNA or RNA molecules under different solution conditions.

Optical tweezers setup for single molecule mechanics measurements in aequeous solutions (own development), high-frequency quasi-peak detector

Typical applications: Study of mechanics and kinetics of folding and binding of single protein, DNA or RNA molecules at high temporal resolution

Single molecule fluorescence microscopy setup, realized in the form of an inverted microscope with objective-type TIRF excitation. Capable of single molecule FRET measurements and super-resolution imaging via DNA-PAINT (excitation wavelengths: 488nm, 532nm, 642nm. Objective: 100x)

Typical applications: DNA nanotechnology and DNA nanorobotics.

For the imaging and biological and non-biological sample topography including environmental control (temperature, aqueous or gaseous), with special cantilevers high-speed scanning possible (> 1 fps), additional imaging modes such as KPFM, MFM, etc., photothermal actuation of cantilever (optional).

Combines Atomic Force Microscopy with optical imaging for imaging and spectroscopy in the visible, infrared and terahertz spectral region at 10 nm spatial resolution.