Instrument: Sp8 Confocal Microscope

Comprises 3 Hyde Detectors, increased resolution by adaptive deconvolution, climate chamber for live cell imaging

Instrument: Multicolor TIRF Microscope with FRAP Laser

Instrument: STORM based superresolution microscope (STORM-GSD)

Instrument: Lumicks Optical Tweezers

Optical tweezers setup for single molecule mechanics measurements in aequeous solutions with integrated microfluidics with in situ change of solution conditions for one single molecule

Typical applications: study of the mechanics and kinetics of folding and binding of single protein, DNA or RNA molecules under different solution conditions.

Instrument: Optical Tweezers with frequency detection, low drift

Optical tweezers setup for single molecule mechanics measurements in aequeous solutions (own development), high-frequency quasi-peak detector

Typical applications: Study of mechanics and kinetics of folding and binding of single protein, DNA or RNA molecules at high temporal resolution

Instrument: DNA PAINT/FRET

Single molecule fluorescence microscopy setup, realized in the form of an inverted microscope with objective-type TIRF excitation. Capable of single molecule FRET measurements and super-resolution imaging via DNA-PAINT (excitation wavelengths: 488nm, 532nm, 642nm. Objective: 100x)

Typical applications: DNA nanotechnology and DNA nanorobotics.

Instrument: AFM Asylum Cypher

For the imaging and biological and non-biological sample topography including environmental control (temperature, aqueous or gaseous), with special cantilevers high-speed scanning possible (> 1 fps), additional imaging modes such as KPFM, MFM, etc., photothermal actuation of cantilever (optional).

Instrument: neaspec neaSNOM

Combines Atomic Force Microscopy with optical imaging for imaging and spectroscopy in the visible, infrared and terahertz spectral region at 10 nm spatial resolution.