Proteomics aims at characterizing the protein content in a given sample at a given time point. The sample origin can be highly diverse, ranging from cellular extracts, tissues, fluids or nutritional samples coming from humans, animals, bacteria, fungi or plants. Depending on the biological question asked, proteomic analyses can be used to:
- identify the proteins in a given sample
- study the nature and position of posttranslational modifications (PTMs)
- measure protein abundance changes between samples (relative quantification)
- measure the protein copy number or absolute amount in a sample (absolute quantification)
- investigate protein complex formation
- characterize protein-ligand or protein-drug interactions
- study protein localization
- investigate protein stability and protein turnover
- study and describe biological networks and protein pathways
Over the last few decades, the rapid development of new proteomic instrumentation as well as proteomic data analysis tools has made liquid chromatography mass spectrometry (LC-MS) based proteomics the method-of-choice to study the complex biological protein networks and pathways in cells or organs, to identify new drug targets, to improve diagnosis and prognosis of diseases and to acquire a better understanding of the ongoing molecular processes in life.
Thanks to its state-of-the-art mass spectrometers and technologies, BayBioMS can provide to its users service and support at all stages of the proteomic analysis workflow. If you want to interact with BayBioMS and have any questions do not hesitate and contact us.